Assessment of safety and adverse events in endoscopic radiofrequency ablation for malignant biliary obstruction
| Autor: | Hayat Khizar, Yufei Hu, Weigang Gu, Jin Yang, Hangbin Jin, Xiayin He, Xiaofeng Zhang, Jianfeng Yang |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Therapeutic Advances in Gastroenterology, Vol 17 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1756-2848 17562848 |
| DOI: | 10.1177/17562848241294002 |
| Popis: | Background: Endoscopic radiofrequency ablation (RFA) is used for the treatment of unresectable malignant biliary obstruction (MBO). The postoperative adverse events associated with RFA treatment have gained importance. Objective: To investigate the early adverse events and their risk factors associated with RFA for the treatment of MBO. Design: Observational retrospective study. Methods: We collected data from patients diagnosed with MBO and treated with endoscopic RFA at our hospital between January 2010 and June 2022. Based on the collected data, the patients were divided into two groups: the adverse event group and the nonadverse event group. Early postoperative adverse events were recorded, and risk factors were assessed. Results: One hundred and twenty patients with MBO underwent endoscopic RFA, with 20 developing adverse events (16.6%; 20/120). Among these, 13 patients (10.8%) developed biliary infection after RFA treatment, while 7 (5.8%) developed acute pancreatitis, and no bleeding or perforation occurred. Type 2 diabetes mellitus, bile duct stricture length >2.5 cm, segmental RFA, and the proportion of patients receiving single stent drainage were all significantly greater in the adverse event group compared to the nonadverse event group ( p |
| Databáze: | Directory of Open Access Journals |
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