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AIM: To study the efficacy and safety of accelerated collagen cross-linking in keratoconus.METHODS: Medical records of keratoconic corneas underwent accelerated collagen cross-linking at King Chulalongkorn Memorial Hospital, Thailand between April 2015 and August 2018 were reviewed. Preoperative and postoperative data at 1a of visual acuity, auto-refraction, corneal topography, higher-order aberrations(HOA), topometric indices and corneal densitometry were evaluated. Age of 24 and 30 years old, maximum keratometry value(Kmax)of 55 D, and baseline best corrected visual acuity(BCVA)of 20/40(or 0.3 in LogMAR unit)were used as cut-off values to highlight the cross-linking effects. The effect of age, preoperative Kmax and BCVA were analyzed. The association between the change of corneal densitometry and other factors including preoperative Kmax, Kmean, manifest refraction spherical equivalent(MRSE), visual acuity, thinnest pachymetry, the change in Kmax, and the change of those parameters were also analyzed. P |
