Levan-Capped Silver Nanoparticles for Bactericidal Formulations: Release and Activity Modelling

Autor: Álvaro González-Garcinuño, Rubén Masa, María Hernández, Ángel Domínguez, Antonio Tabernero, Eva Martín del Valle
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Molecular Sciences, Vol 20, Iss 6, p 1502 (2019)
Druh dokumentu: article
ISSN: 1422-0067
DOI: 10.3390/ijms20061502
Popis: An environmentally friendly technique was used to produce levan-capped silver nanoparticles of about 30 nm (with a loading of 30%) that showed bactericide effect, for E. coli and B. subtilis. That effect was mathematically studied with a dose-response model (lethal dose of 12.4 ppm and 6.8 ppm respectively). These silver nanoparticles were subsequently introduced in a gel to create a silver release system with bacteria inhibition activity. Silver release from the gel and its bactericidal activity was theoretically studied to develop a unique model that is able to predict accurately both silver release and lethal dose for any type of bacteria. This model will be useful for performing predictions for future silver in gel applications.
Databáze: Directory of Open Access Journals
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