| Autor: |
Hiu Fung Wu, Ellen Lok Man Yu, Bun Sheng, Kwok Kui Wong, Man Au Yeung, Wa Tai Wong, Hon Hang Kwan, Lun Pei Ng, Chun Hin Cheung, Yan Lok Lam, Yat Kwan Chan |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Clinical Parkinsonism & Related Disorders, Vol 10, Iss , Pp 100235- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2590-1125 |
| DOI: |
10.1016/j.prdoa.2024.100235 |
| Popis: |
Objective: To assess the incidence of Impulse control and related behavioral disorders (ICRD) in Chinese Idiopathic Parkinson Disease (IPD) patients treated with different dopamine agonists (DA), and their clinical characteristics and associated risk factors. Methods: This was an observational cohort study based on clinical interviews and medical records of IPD patients treated with DA for >6 months in three hospitals in Hong Kong. The short version of Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease (QUIP-S) was used to screen for ICRD. ICRD incidence among different DA, clinical characteristics and risk factors were examined. Results: Incidence of ICRD was analyzed in 311 patients taking their first, single DA. 43 patients (13.8 %) developed ICRD. The mean duration of IPD was 8.5 ± 5.6 years and median HY stage was 2.5. Bromocriptine and rotigotine users had lower ICRD incidence rate. Both pramipexole [adjusted HR 7.28 (2.46–21.54), p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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