Exclusive and Solitary Facial Porokeratosis: Pathogenesis and Literature Reappraisal of a Rare Entity

Autor: Giovanni Paolino, Matteo Riccardo Di Nicola, Marina Yarygina, Carlo Mattozzi, Eduardo Quaranta, Vittoria Giulia Bianchi, Michele Donati, Santo Raffaele Mercuri
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Case Reports in Dermatology, Vol 15, Iss 1, Pp 147-151 (2023)
Druh dokumentu: article
ISSN: 1662-6567
DOI: 10.1159/000530936
Popis: Porokeratosis is a group of well-known clinically distinct entities, characterised by different clinical aspects, but sharing a single common histological aspect, namely the cornoid lamella. Usually, porokeratosis occurs in the limbs and trunk, while it rarely involves the face, especially as an exclusive, single, and solitary lesion. We report the case of a 52-year-old Caucasian woman, with an 11-month history of a 2-cm slowly growing solitary, keratotic lesion on her left cheekbone. The patient did not present other cutaneous lesions on the face, as well as in other body sites. A cutaneous biopsy showed epidermal hyperplasia with multiple, sharply defined cornoid lamella, associated with an underlying attenuation of the granular layer and scattered dyskeratotic cells in the spinous layer. The superficial dermis underneath showed a mild lymphocytic infiltrate and fibrosis with remodelled collagen bundles. A final diagnosis of solitary facial porokeratosis was made.
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