AGE-RELATED CHANGES IN HEART RATE VARIABILITY AND THEIR RELATION WITH LEUCOCYTE TELOMERE LENGTH
| Autor: | L. I. Streltsova, О. N. Tkacheva, E. V. Plokhova, D. U. Akasheva, I. D. Strajesko, E. N. Dudinskaya, S. А. Boytsov |
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| Jazyk: | ruština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 16, Iss 1, Pp 54-60 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1728-8800 2619-0125 |
| DOI: | 10.15829/1728-8800-2017-1-54-60 |
| Popis: | Aim. To assess the relation of age-depended changes in heart rate variability (HRV) with telomere length. With the age, even with no cardiovascular diseases (CVD), there is a decline of HRV which is an indicator of vegetative system condition. The probable mechanism for age-related decrease in HRV might be cellular ageing. One of the markers of cellular ageing is telomere length regarded as a marker of biological age.Material and methods. Totally, 229 persons of age 23-91 y.o. included, with no clinical signs of cardiovascular diseases. All participants underwent the HRV analysis by the data of Holter ECG monitoring and of short ECG recordings supine and upright position by 5 minutes. Telomere length was assessed in leucocytes on genomic desoxyribonucleic acid (DNA) with plymeraze chain reaction real time. The participants were selected to two groups: |
| Databáze: | Directory of Open Access Journals |
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