Patient with frontal-variant syndrome in early-onset Alzheimer's disease

Autor: Xia Li, Shifu Xiao, Lin Sun, Han Cai, Su Ning
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: General Psychiatry, Vol 33, Iss 2 (2020)
Druh dokumentu: article
ISSN: 2517-729X
DOI: 10.1136/gpsych-2019-100173
Popis: The clinical manifestation of frontal-variant Alzheimer’s disease (fvAD) is not typical, and it is difficult yet necessary to differentiate fvAD from frontal-variant frontal temporal dementia (fvFTD). We describe a patient with early-onset Alzheimer’s disease (AD) who presented with an fvFTD-like syndrome and apolipoprotein E ɛ3/ ɛ4 genotype. A brain amyloid imaging procedure, 11C-Pittsburgh compound B positron emission tomography (PET), supported the final diagnosis of AD. Our present case highlights the clinical variability that characterises early-onset AD. A multimodal approach is crucial when assessing rare forms of dementia.
Databáze: Directory of Open Access Journals