Differentially expressed genes in the femur cartilage transcriptome clarify the understanding of femoral head separation in chickens

Autor: Ludmila Mudri Hul, Adriana Mércia Guaratini Ibelli, Igor Ricardo Savoldi, Débora Ester Petry Marcelino, Lana Teixeira Fernandes, Jane Oliveira Peixoto, Maurício Egídio Cantão, Roberto Hiroshi Higa, Poliana Fernanda Giachetto, Luiz Lehmann Coutinho, Mônica Corrêa Ledur
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-97306-3
Popis: Abstract Locomotor problems are among one of the main concerns in the current poultry industry, causing major economic losses and affecting animal welfare. The most common bone anomalies in the femur are dyschondroplasia, femoral head separation (FHS), and bacterial chondronecrosis with osteomyelitis (BCO), also known as femoral head necrosis (FHN). The present study aimed to identify differentially expressed (DE) genes in the articular cartilage (AC) of normal and FHS-affected broilers by RNA-Seq analysis. In the transcriptome analysis, 12,169 genes were expressed in the femur AC. Of those, 107 genes were DE (FDR
Databáze: Directory of Open Access Journals
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