SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations.

Autor: Dongzhu Ma, Anna Jasinska, Jan Kristoff, J Paul Grobler, Trudy Turner, Yoon Jung, Christopher Schmitt, Kevin Raehtz, Felix Feyertag, Natalie Martinez Sosa, Viskam Wijewardana, Donald S Burke, David L Robertson, Russell Tracy, Ivona Pandrea, Nelson Freimer, Cristian Apetrei, International Vervet Research Consortium
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS Pathogens, Vol 9, Iss 1, p e1003011 (2013)
Druh dokumentu: article
ISSN: 1553-7366
1553-7374
DOI: 10.1371/journal.ppat.1003011
Popis: Pathogenesis studies of SIV infection have not been performed to date in wild monkeys due to difficulty in collecting and storing samples on site and the lack of analytical reagents covering the extensive SIV diversity. We performed a large scale study of molecular epidemiology and natural history of SIVagm infection in 225 free-ranging AGMs from multiple locations in South Africa. SIV prevalence (established by sequencing pol, env, and gag) varied dramatically between infant/juvenile (7%) and adult animals (68%) (p
Databáze: Directory of Open Access Journals