Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?

Autor: Mehtap Doğan, Kasım Durmuş, Zekiye Hasbek, Emine Elif Altuntaş
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Otology, Vol 13, Iss 1, Pp 20-24 (2018)
Druh dokumentu: article
ISSN: 1672-2930
DOI: 10.1016/j.joto.2017.10.001
Popis: Objective: The objective of this study was to examine the effect of hypothyroidism on hearing function in patients surgically treated for differentiated thyroid cancer and subsequently experienced hypothyroidism during preparation for follow up I-131 scintigraphy scan by either recombinant human thyroid stimulating hormone (rhTSH) treatment or thyroid hormone withdrawal (THW). Methods: A total of 55 patients undergoing I-131 scintigraphy scan following surgeries for differentiated thyroid cancer were included in the study, including 25 patients prepared by administration of recombinant TSH (rhTSH Group) and 30 patients by thyroid hormone withdrawal (THW Group). Results: Air conduction thresholds at 1, 2 and 4 kHz for both ears were higher during hypothyroid period than during euthyroid period for patients in the THW group (p
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