Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia

Autor: Li Jiang, Wei Wei, Sheng Kang, Xiao-Lin Li, Yu Luo
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Physiology, Vol 14 (2023)
Druh dokumentu: article
ISSN: 1664-042X
DOI: 10.3389/fphys.2023.1096991
Popis: Coronary artery ectasia (CAE) is a rare finding that is associated with poor clinical outcomes (Kawsara et al. 2018), and disorders in lipid metabolism have been reported in CAE. Lipids constitute one of the three metabolite types that regulate bodily functions and are also powerful signaling molecules (Han 2016; Zhu et al. 2021) that affect immunoregulation and inflammatory responses via a series of transcription factors and signaling pathways (Barrera et al. 2013). Although abnormal lipid metabolism and immunoinflammatory responses have been reported in CAE, their roles in the pathogenic mechanisms underlying CAE are currently unclear.
Databáze: Directory of Open Access Journals