Low dosis of alteplase, for ischemic stroke after Enchanted and its determinants, a single center experience
| Autor: | Alejandro Michel Brunser, Enrico Mazzon, Gabriel Cavada, Eloy Mansilla, Alexis Rojo, Juan Almeida, Verónica Viviana Olavarría, Paula Muñoz-Venturelli, Pablo Manuel Lavados |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Arquivos de Neuro-Psiquiatria, Vol 78, Iss 11, Pp 681-686 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1678-4227 0004-282x |
| DOI: | 10.1590/0004-282x20200048 |
| Popis: | Abstract Background: Low-dose alteplase (LrtPA) has been shown not to be inferior to the standard-dose (SrtPA) with respect to death/disability. Objective: We aim to evaluate the percentage of patients treated with LrtPA at our center after the ENCHANTED trial and the factors associated with the use of this dosage. Methods: Prospective study in consecutive patients with an acute stroke admitted between June 2016 and November 2018. Results: 160 patients were treated with intravenous thrombolysis, 50% female; mean age 65.4±18.5 years. Of these, 48 patients (30%) received LrtPA. In univariate analysis, LrtPA was associated with patient's age (p=0.000), previous modified Rankin scale scores (mRS) (p |
| Databáze: | Directory of Open Access Journals |
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