The molecular basis, genetic control and pleiotropic effects of local gene co-expression

Autor: Diogo M. Ribeiro, Simone Rubinacci, Anna Ramisch, Robin J. Hofmeister, Emmanouil T. Dermitzakis, Olivier Delaneau
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-25129-x
Popis: Local gene co-expression is found throughout the genome, but systematic analysis of these co-expressed genes is needed. Here, the authors identify local co-expressed genes in 49 tissues and characterize the genetic variants which may affect their expression and contribute to disease.
Databáze: Directory of Open Access Journals