| Autor: |
E. G. Lomaia, E. G. Romanova, E. I. Sbityakova, A. Yu. Zaritskiy |
| Jazyk: |
ruština |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Онкогематология, Vol 8, Iss 2, Pp 22-33 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1818-8346 |
| Popis: |
Current treatment options for chronic myeloid leukemia (CML) with imatinib allowed achieving long-term progression-free and overall survival and improved patient quality of life. In cases of imatinib resistance therapy with second-generation tyrosine kinases inhibitors – dasatinib and nilotinib – is also possible. The article represents a literature review evaluating efficacy and toxicity of both drugs and highlighting some of the practical issues of CML treatment after first-line therapy failure. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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