Predictors of atrial fibrillation detection in embolic stroke of undetermined source patients with implantable loop recorder

Autor: Lucio D’Anna, Roberta La Cava, Ashni Khetarpal, Abeer Karjikar, Ahmad Almohtadi, Michele Romoli, Matteo Foschi, Raffaele Ornello, Federico De Santis, Simona Sacco, Samir Abu-Rumeileh, Simone Lorenzut, Daisy Pavoni, Mariarosaria Valente, Giovanni Merlino, Soraia Almeida, Asha Barnard, Jianqun Guan, Soma Banerjee, Phang Boon Lim
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2024.1369914
Popis: BackgroundCovert atrial fibrillation (AF) is a predominant aetiology of embolic stroke of undetermined source (ESUS). Evidence suggested that AF is more frequently detected by implantable loop recorder (ILR) than by conventional monitoring. However, the predictive factors associated with occult AF detected using ILRs are not well established yet. In this study we aim to investigate the predictors of AF detection in patients with ESUS undergoing an ILR.MethodsThis observational multi-centre study included consecutive ESUS patients who underwent ILR implantation. The infarcts were divided in deep, cortical infarcts or both. The infarction sites were categorized as anterior and middle cerebral artery, posterior cerebral artery with and without brainstem/cerebellum involvement. Multivariable logistic regression analysis was performed to investigate variables associated with AF detection.ResultsOverall, 3,000 patients were initially identified. However, in total, 127 patients who consecutively underwent ILR implantation were included in our analysis. AF was detected in 33 (26%) out of 127 patients. The median follow-up was 411 days. There were no significant differences in clinical characteristics and comorbidities between patients with and without AF detected. AF was detected more often after posterior cerebral artery infarct with brainstem/cerebellum involvement (p
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