Cellulosimicrobium Infections in Humans—A Narrative Review

Autor: Petros Ioannou, Alexandra Vorria, George Samonis
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Antibiotics, Vol 13, Iss 6, p 562 (2024)
Druh dokumentu: article
ISSN: 13060562
2079-6382
DOI: 10.3390/antibiotics13060562
Popis: Cellulosimicrobium species (formerly known as Oerskovia) are Gram-positive filamentous bacteria in the family Promicromonosporaceae and are more commonly found in sewage and soil. The present study aimed to identify all the published cases of Cellulosimicrobium species infections in the literature, describe the epidemiological, clinical, and microbiological characteristics, and provide data regarding its antimicrobial resistance, treatment, and outcomes. A narrative review was performed based on a PubMed and Scopus database search. In total, 38 studies provided data on 40 patients with infections by these species. The median age of patients was 52.5 years, and 55% were male. The most common infection types were bacteremia, infective endocarditis (IE), osteoarticular infections, peritoneal dialysis-associated peritonitis, and endophthalmitis. Antimicrobial resistance to vancomycin and the combination of trimethoprim and sulfamethoxazole was minimal, and vancomycin was the most commonly used antimicrobial for treating these infections. Overall mortality was minimal for all infections, except for bacteremia and IE, which carried high mortality rates.
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