Updates in Pathology for Retroperitoneal Soft Tissue Sarcoma

Autor:	Tanner Mack, Bibianna Purgina
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	retroperitoneum sarcoma molecular liposarcoma leiomyosarcoma GIST Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Current Oncology, Vol 29, Iss 9, Pp 6400-6418 (2022)
Druh dokumentu:	article
ISSN:	29090504 1718-7729 1198-0052
DOI:	10.3390/curroncol29090504
Popis:	Retroperitoneal tumors are extremely rare. More than 70% of primary retroperitoneal soft tissue tumors are malignant. The most common sarcomas in the retroperitoneum include liposarcomas and leiomyosarcoma, however other sarcomas, along with benign mesenchymal tumors, can occur. Sarcomas are a heterogenous group of tumors with overlapping microscopic features, posing a diagnostic challenge for the pathologist. Correct tumor classification has become important for prognostication and the evolving targeted therapies for sarcoma subtypes. In this review, the pathology of retroperitoneal soft tissue sarcomas is discussed, which is important to the surgical oncologist. In addition, less common sarcomas and benign mesenchymal tumors of the retroperitoneum, which may mimic sarcoma clinically and pathologically, are also discussed.
Databáze:	Directory of Open Access Journals
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