Cytomegalovirus cavitary pneumonia in a human immunodeficiency virus‐infected patient

Autor: Yusuke Sunanaga, Takayuki Suetsugu, Yusuke Nagata, Marina Miyata, Kiyotaka Kondo, Hideo Mitsuyama, Shingo Kubota, Keiko Mizuno, Kentaro Tanaka, Hiromasa Inoue
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Respirology Case Reports, Vol 12, Iss 5, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2051-3380
30117194
DOI: 10.1002/rcr2.1392
Popis: Abstract Cavitary lung lesions are uncommon radiological findings in cytomegalovirus pneumonia, and tissue biopsy is rarely performed for diagnosis. A 67‐year‐old man presented with a wet cough. Extensive white moss in the oral cavity was found on physical examination, and chest computed tomography revealed an approximately 4 cm cavitary lesion in the upper lobe of the right lung. Blood tests showed a critically low CD4+ T lymphocyte count and positivity for human immunodeficiency virus type 1 antibodies. A transbronchial biopsy of the cavitary lung lesion was performed, and inclusion bodies in the nuclei of enlarged alveolar epithelial cells were seen in the histopathological findings. Immunohistochemistry staining for cytomegalovirus was positive, and cytomegalovirus pneumonia was diagnosed. Ganciclovir treatment was initiated, and the symptoms and imaging findings resolved. Cytomegalovirus pneumonia can present as cavitary lung lesions in patients with acquired immunodeficiency syndrome, and a transbronchial biopsy is essentially useful for a definitive diagnosis.
Databáze: Directory of Open Access Journals
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