| Autor: |
Simon Erridge, Ophilia Leung, Carl Holvey, Ross Coomber, Sushil Beri, Shaheen Khan, Mark W. Weatherall, James J. Rucker, Michael W. Platt, Mikael H. Sodergren |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Neuropsychopharmacology Reports, Vol 43, Iss 4, Pp 616-632 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2574-173X |
| DOI: |
10.1002/npr2.12403 |
| Popis: |
Abstract Introduction While there is increasing evidence of the effects of cannabis‐based medicinal products (CBMPs) on health‐related quality of life (HRQoL), a major limitation of the current literature is the heterogeneity of studied CBMPs. This study aims to analyze changes in HRQoL in patients prescribed a homogenous selection of CBMPs. Methods Primary outcomes were changes in patient‐reported outcomes (PROMs) at 1, 3, 6, and 12 months from baseline. The secondary outcome was an adverse events analysis. Statistical significance was defined as p 0.050). 3663 (265.82%) adverse events were reported by 297 (21.55%) patients. Conclusion There was an associated improvement in self‐reported anxiety, sleep quality, and HRQoL in patients treated with the CBMPs. Those prescribed treatment formulations including dried flower were most likely to show a clinical improvement. However, these results must be interpreted with caution given the limitations of study design. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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