Substitute parameters of exercise-induced pulmonary hypertension and usefulness of low workload exercise stress echocardiography in mitral regurgitation

Autor: Masashi Amano, Shoko Nakagawa, Kenji Moriuchi, Hitomi Nishimura, Yurie Tamai, Ayaka Mizumoto, Yoshiki Yanagi, Rika Yonezawa, Yutaka Demura, Yoshito Jo, Yuki Irie, Atsushi Okada, Takeshi Kitai, Makoto Amaki, Hideaki Kanzaki, Kengo Kusano, Teruo Noguchi, Kunihiro Nishimura, Chisato Izumi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-19987-8
Popis: Abstract In asymptomatic patients with mitral regurgitation (MR), data of exercise-induced pulmonary hypertension (EIPH) are limited, and feasibility of evaluating EIPH is not high. We aimed to investigate prognostic impact of EIPH and its substitute parameters. Exercise stress echocardiography (ESE) were performed in 123 consecutive patients with moderate to severe degenerative MR. The endpoint was a composite of death, hospitalization for heart failure, and worsening of symptoms. EIPH [tricuspid regurgitation peak gradient (TRPG) at peak workload ≥ 50 mmHg] was shown in 57 patients (46%). TRPG at low workload was independently associated with TRPG at peak workload (β = 0.67, p
Databáze: Directory of Open Access Journals
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