Treatment of keloids: a literature review
| Autor: | Pedro Martins Corrêa, Camila Eugênia Fonseca Passos, Eduardo Mesquita de Souza, Guilherme Augusto Sousa Batista, Jéssica De Oliveira Jacintho, Luiza Barbosa de Oliveira, Oscar Campos Lisboa, Joyce de Sousa Fiorini Lima |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Revista Brasileira de Cirurgia Plástica, Vol 34, Iss 03, Pp 391-398 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1983-5175 2177-1235 |
| DOI: | 10.5935/2177-1235.2019RBCP0213 |
| Popis: | Introduction: Keloids are characterized by an abnormal response to dermal trauma, resulting in fibroblast proliferation, excessive collagen production, and impairment of adjacent healthy tissue. The diagnosis is clinical, and many conservative and surgical methods can be used as treatments. However, data on the efficacy of these treatments are limited, and there is no consensus regarding the best treatment option. This gap needs to be filled by developing comprehensive evidence-based therapies. Methods: A non-systematic literature review of keloid scars was carried out using PubMed, Scielo, MEDLINE, UptoDate, and dermatology and dermatological surgery textbooks. Literature review: The search retrieved relevant information on surgical and adjuvant therapies used for keloids, including excision, intralesional injections, cryotherapy, laser therapy, silicone gel sheeting, radiation therapy, and pressure therapy. These data are crucial because, in addition to complaints of pain, itching, and restriction of movement, the main reason for seeking treatment for keloids is for cosmetic and aesthetic improvement, and the rates of recurrence and treatment failure are high, emphasizing the importance of creating awareness regarding the available procedures and their effectiveness. Conclusion: Many surgical and adjuvant therapies for keloids are available. Nonetheless, there is no consensus on a universally accepted treatment. Therefore, additional high-quality studies are needed to identify the most effective therapeutic approaches to achieve better results. |
| Databáze: | Directory of Open Access Journals |
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