ANALYSIS OF THE VALUES OF OXIDATIVE STRESS PARAMETERS IN SALIVA OF CHILDREN WITH GINGIVITIS
| Autor: | Olivera Tričković-Janjić, Tatjana Cvetković, Marija Igić, Branislava Stojković, Mila Janjić, Gordana Filipović |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Acta Medica Medianae, Vol 55, Iss 2, Pp 12-18 (2016) |
| Druh dokumentu: | article |
| ISSN: | 0365-4478 1821-2794 |
| DOI: | 10.5633/amm.2016.0202 |
| Popis: | Early detection and analysis of the values of the parameters of oxidative stress, malondialdehyde (MDA) and reactive carbonyl groups (RCG) in saliva, as possible biochemical markers in the diagnosis and prognosis of periodontal disease, may be of particular importance in children. For this reason, the aim of this study was to examine the levels of lipoproteins in the saliva of children without gingivitis and with gingivitis, as well as the degree of gingival inflammation. The testing was conducted in 120 children aged 12.2 years, with permanent dentition. Gingival index by Löe-Silness was used for the gingival estimation. A modified method with thiobarbituric acid was used for the determination of MDA in unstimulated saliva. Colorimetric reaction with 2.4 dinitrophenylhydrazine (2.4 DNPH) was applied for the determination of RCG. Results of the analysis of the average values of prooxidizer in the saliva of the patients in a study and the control group showed as statistically significantly higher in the patients of the study group, in RCG concentration (UMW=667.5, z=-4.137, p |
| Databáze: | Directory of Open Access Journals |
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