The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays

Autor: María Bayona-Caballero, Judith Alayo-Zavaleta, César Lombardi-Pérez, Carmen Marín-Tello
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2020
Předmět:
Zdroj: Ars Pharmaceutica, Vol 60, Iss 4, Pp 213-218 (2020)
Druh dokumentu: article
ISSN: 2340-9894
DOI: 10.30827/ars.v60i4.10226
Popis: Abstract Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium.
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