Autor: |
María Bayona-Caballero, Judith Alayo-Zavaleta, César Lombardi-Pérez, Carmen Marín-Tello |
Jazyk: |
English<br />Spanish; Castilian |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Ars Pharmaceutica, Vol 60, Iss 4, Pp 213-218 (2020) |
Druh dokumentu: |
article |
ISSN: |
2340-9894 |
DOI: |
10.30827/ars.v60i4.10226 |
Popis: |
Abstract Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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