Short-term results of intra-articular injections of stromal vascular fraction for early knee osteoarthritis

Autor: Cristian Aletto, Lorenzo Giordano, Marco Quaranta, Arnaldo Zara, Donato Notarfrancesco, Nicola Maffulli
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 1749-799X
DOI: 10.1186/s13018-022-03196-0
Popis: Abstract Background In knee osteoarthritis, progressive degeneration of the articular cartilage surface produces disability and chronic pain. Intra-articular injections of stromal vascular fraction (SVF) could be an innovative approach to manage patients with early knee osteoarthritis. Methods Between June 2019 and November 2020, 123 patients were recruited to receive intra-articular injection of SVF. Radiographic evidence of degenerative joint disease was classified according to Kellgren and Lawrence grades. Knee injury and osteoarthritis outcome score (KOOS) and visual analog scale (VAS) were collected preoperatively, at 1 month, and after 6 months from injection. Results There was a statistically significant improvement of KOOS and VAS of all patients to 6 months (p
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