Treatment and monitoring of children and adolescents with hepatitis C in Russia: Results from a multi-centre survey on policy and practice

Autor: Farihah Malik, Vladimir Chulanov, Nikolay Pimenov, Anastasia Fomicheva, Rebecca Lundin, Nataliia Levina, Claire Thorne, Anna Turkova, Giuseppe Indolfi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Virus Eradication, Vol 8, Iss 1, Pp 100063- (2022)
Druh dokumentu: article
ISSN: 2055-6640
DOI: 10.1016/j.jve.2022.100063
Popis: Background: The Russian Federation has the largest paediatric hepatitis C virus (HCV) disease burden in the World Health Organization European region with an estimated 118,000 children living with HCV viraemia. Direct-acting antivirals (DAAs) have been available for adults in Russia since 2015 and approved for treatment of adolescents aged ≥12 years since 2019. We evaluated DAA availability and uptake for HCV treatment of children and adolescents and clinical practices on diagnosis and management of paediatric HCV in Russia. Methods: A survey was distributed to regional ministries of health in 85 administrative regions during September 2020. The survey consisted of 22 items collecting data on: type of facility, aggregate patient characteristics, HCV testing practices for children and pregnant women and HCV management and treatment practices for children. Results: Survey responses were received from 37 of the 85 regions in Russia (response rate 44%). 2159 children and adolescents with chronic HCV were in follow-up; 1089 (50%) were female. Of 2080 children with available data on age-groups, 134 (6%) were
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