Biological Effective Radiation Dose for Multiple Myeloma Palliation

Autor: Ruby F. Meredith, MD, PhD, John R. Bassler, MS, Andrew M. McDonald, MD, John M. Stahl, MD, David T. Redden, PhD, James A. Bonner, MD
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101214- (2023)
Druh dokumentu: article
ISSN: 2452-1094
DOI: 10.1016/j.adro.2023.101214
Popis: Purpose: Various radiation therapy (RT) dose/fractionation schedules are acceptable for palliation in multiple myeloma. Nine years of single-institution RT experience were reviewed to determine the influence of dose/fractionation and other factors pertinent to individualizing therapy. Methods and Materials: In total, 152 items were identified from Current Procedural Terminology codes for multiple myeloma treatment from 2012 through June 30, 2021. After exclusions, 205 sites of radiation in 94 patients were reviewed. Data were captured from treatment planning and clinical records. To statistically assess the association between biological effective dose (BED10) and variables of interest, BED was first dichotomized to
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