Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer

Autor: Haoxing D. Jin, Nathan W. Blessing
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: American Journal of Ophthalmology Case Reports, Vol 19, Iss , Pp 100810- (2020)
Druh dokumentu: article
ISSN: 2451-9936
DOI: 10.1016/j.ajoc.2020.100810
Popis: Purpose: To report a case of cicatricial ectropion and madarosis with the use of anti-epidermal growth factor receptor medication panitumumab. Observations: An 82-year-old man with metastatic colorectal cancer presented with cicatricial ectropion and madarosis after starting panitumumab, an anti-epidermal growth factor receptor medication used to treat metastatic colorectal cancer. His findings resolved several weeks after discontinuation of panitumumab and treatment with lubrication and antibiotic/steroid ointment. Conclusion: This case demonstrates the importance to consider potential medication side effects when treating periocular conditions in patients taking anti-epidermal growth factor receptor (anti-EGFR) agents.
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