Alkaloid binding to opium poppy major latex proteins triggers structural modification and functional aggregation

Autor: Natali Ozber, Samuel C. Carr, Jeremy S. Morris, Siyu Liang, Jacinta L. Watkins, Kristian M. Caldo, Jillian M. Hagel, Kenneth K. S. Ng, Peter J. Facchini
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-34313-6
Popis: Opium poppy accumulates alkaloids in the specialized cytoplasm of laticifers known as latex. Here the authors show that the binding of alkaloids to the abundant major latex proteins triggers quaternary structural modification that mediates a functional role for protein aggregation.
Databáze: Directory of Open Access Journals