Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation

Autor: Arif E. Cetin, Mark M. Stevens, Nicholas L. Calistri, Mariateresa Fulciniti, Selim Olcum, Robert J. Kimmerling, Nikhil C. Munshi, Scott R. Manalis
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-01593-2
Popis: Multiple myeloma is characterized by high rates of drug resistance and relapse. Here the authors utilize a functional assay to assess the ex vivo drug sensitivity of single multiple myeloma cells based on measuring the mass accumulation rate of individual cells.
Databáze: Directory of Open Access Journals