Factors related to the absorption rate of benign thyroid nodules after image-guided microwave ablation: a 3-year follow-up

Autor: Li-Hong Liu, Bei-Bei Yang, Ying Liu, Jin-Ling Wang, Dan-Dan Wang, Hong-Yu Ding, Shu-Rong Wang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Hyperthermia, Vol 39, Iss 1, Pp 8-14 (2022)
Druh dokumentu: article
ISSN: 0265-6736
1464-5157
02656736
DOI: 10.1080/02656736.2021.1995632
Popis: Purpose To assess the absorption rate and factors related to the development of benign thyroid nodules (BTNs) following image-guided microwave ablation (MWA). Materials and methods This retrospective study reviewed nodule efficacy in patients who underwent MWA of BTNs between January 2016 and January 2018. The endpoint was a third-year follow-up. Nodules were categorized into those showing complete absorption (volumes with less than 100% volume reduction ratio (VRR) and those showing partial absorption (100% VRR)). Univariable and multivariable regression analyses were carried out to identify variables that were associated with nodule absorption rates. Results A total of 173 BTNs (median volume= 4.23 ml; 25–75 percentiles= 2.27–9.00 ml) from 173 patients were evaluated. 49.7% (86/173) of patients had nodules that became completely absorbed. The mean VRRs of all BTNs were 18.0%, 78.7%, 89.0%, 94.5%, and 97.1% at the 1-, 6-,12-, 24- and 36- month follow-ups. At the 3-year follow-up time point, nodule characteristics related to nodule VRR included nodule volume (adjusted odds ratio [AOR], 1.1 [95% CI: 1.0, 1.2]; p = 0.03) and nodule margin (AOR, 5.3 [95% CI: 1.8, 16.0]; p
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