Serum malondialdehyde, monocyte chemoattractant protein-1, and vitamin C levels in wet type age-related macular degeneration patients
| Autor: | Ramazan Kürşad Zor, Serpil Erşan, Erkut Küçük, Gamze Yıldırım, İsmail Sarı |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Therapeutic Advances in Ophthalmology, Vol 12 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2515-8414 25158414 |
| DOI: | 10.1177/2515841420951682 |
| Popis: | Purpose: The purpose of this study was to investigate the serum levels of malondialdehyde (MDA) which is a marker of oxidative stress, monocyte chemoattractant protein-1 (MCP-1) which has an important role in inflammation, and vitamin C which has antioxidant properties in patients with wet age-related macular degeneration (wAMD). Methods: Thirty patients with wAMD were included in the study and serum levels of MDA, MCP-1, and vitamin C were compared with healthy participants ( n = 30). Serum vitamin C and MDA levels were measured using a spectrophotometric method. Serum MCP-1 levels were determined by the ELISA method. Results: MCP-1 and MDA levels were higher in patients with wAMD compared with the control group ( p |
| Databáze: | Directory of Open Access Journals |
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