Lethal Melanomas: A Population-based Registry Study in Western Sweden from 1990 to 2014

Autor: Magdalena Claeson, Martin Gillstedt, David C. Whiteman, John Paoli
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Acta Dermato-Venereologica, Vol 97, Iss 10, Pp 1206-1211 (2017)
Druh dokumentu: article
ISSN: 0001-5555
1651-2057
00015555
DOI: 10.2340/00015555-2758
Popis: The incidence rates of thin melanomas (≤1 mm Breslow thickness) have increased in many fair-skinned populations, prompting a need to better identify patients with thin melanomas who will eventually die from the disease. This study aimed to describe the clinicopathological characteristics of lethal melanomas in Western Sweden, with a focus on thin lesions. Population-based data on invasive melanomas diagnosed during the years 1990 to 2014 were extracted from the Swedish Melanoma Registry, and linked to the Swedish Cause of Death Registry. The age-standardized incidence (US population 2000) of thin melanomas increased from 9.1×10–5 (95% confidence interval (95% CI) 8.5–9.8) to 21.3×10–5 (95% CI 20.4–22.1) during the study period. Thin melanomas comprised 55.2% of the total and contributed to 13.5% of all melanoma deaths. Non-ulcerated melanomas 0.76–1 mm and ulcerated melanomas 0.26–1.0 mm showed a poorer survival compared with other thin melanomas.
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