| Autor: |
Radhe S Nai, Bhikam C Ghiya, Alpana K Mohta, Rajesh D Mehta |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Journal of Cutaneous and Aesthetic Surgery, Vol 15, Iss 3, Pp 249-253 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
0974-2077 |
| DOI: |
10.4103/JCAS.JCAS_198_21 |
| Popis: |
Background: Molluscum contagiosum (MC) is a common self-limiting viral infection of the skin. Many therapeutic agents have been used for it with varying success rates. Objective: To evaluate and compare the efficacy and safety profile of topical 20% glycolic acid and 30% salicylic acid in the treatment of MC in pediatric patients. Materials and Methods: All patients of MC between 1 and 15 years of age attending the outpatient department of dermatology were randomized into two treatment groups A and B. Group A was treated with 20% glycolic acid solution, and group B was treated with 30% salicylic acid solution daily for 4 weeks. Parents of patients were instructed to apply the medication once daily at night for 1 h on the lesions only. The assessment of response and side effects were analyzed in all the patients weekly for 4 weeks during the daily treatment protocol. Follow-up was done monthly for 3 months after the completion of therapy. Results: At the end of 4 weeks, group A patients (60 patients) were treated with 20% glycolic acid out of which 34 (56.66%) patients had a complete clearance of lesions. Group B patients were treated with 30% salicylic acid out of which 38 (63.33%) had a complete clearance of lesions. Secondary bacterial infection was the most common side effect followed by postinflammatory hyperpigmentation in both groups. Conclusion: 30% salicylic acid was found to be more effective and has less side-effect profile in the treatment of MC than 20% glycolic acid. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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