Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

Autor: Svenja Weiss, Vincenza Itri, Ruimin Pan, Xunqing Jiang, Christina C. Luo, Lynn Morris, Delphine C. Malherbe, Philip Barnette, Jeff Alexander, Xiang-Peng Kong, Nancy L. Haigwood, Ann J. Hessell, Ralf Duerr, Susan Zolla-Pazner
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-28450-1
Popis: Here the authors show that an HIV vaccine in non-human primates that focuses antibodies on the V1V2 region of gp120 is superior to infection or immunization with whole envelope vaccines for inducing V1V2 antibodies with anti-viral functions that correlate with protection.
Databáze: Directory of Open Access Journals
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