| Autor: |
Raul Velez-Montoya, J. Abel Ramirez-Estudillo, Carl Sjoholm-Gomez de Liano, Francisco Bejar-Cornejo, Jorge Sanchez-Ramos, Jose Luis Guerrero-Naranjo, Virgilio Morales-Canton, Sergio E. Hernandez-Da Mota |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
International Journal of Retina and Vitreous, Vol 4, Iss 1, Pp 1-9 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2056-9920 |
| DOI: |
10.1186/s40942-018-0111-5 |
| Popis: |
Abstract Background To assess closure rate after a single surgery of large macular holes and their visual recovery in the short term with three different surgical techniques. Methods Prospective multicenter randomized controlled trial. We included treatment-naïve patients with diagnosis of large macular hole (minimum diameter of > 400 µm). All patients underwent a comprehensive ophthalmological examination. Before surgery, the patients were randomized into three groups: group A: conventional internal limiting membrane peeling, group B: inverted-flap technique and group C: free-flap technique. All study measurements were repeated within the period of 1 and 3 months after surgery. Continuous variables were assessed with a Kruskal–Wallis test, change in visual acuity was assessed with analysis of variance for repeated measurements with a Bonferroni correction for statistical significance. Results Thirty-eight patients were enrolled (group A: 12, group B: 12, group C: 14). The closure rate was in group A and B: 91.6%; 95% CI 61.52–99.79%. In group C: 85.71%; 95% CI 57.19–98.22%. There were no differences in the macular hole closure rate between groups (p = 0.85). All groups improved ≈ 0.2 logMAR, but only group B reached statistical significance (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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