The TFIIH Subunit p89 (XPB) Localizes to the Centrosome during Mitosis
| Autor: | Achim Weber, Hye-Jung Chung, Erik Springer, Dirk Heitzmann, Richard Warth |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Cellular Oncology, Vol 32, Iss 1-2, Pp 121-130 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1570-5870 1875-8606 |
| DOI: | 10.3233/CLO-2009-0509 |
| Popis: | Background: The general transcription factor II H (TFIIH), comprised of a core complex and an associated CAK-complex, functions in transcription, DNA repair and cell cycle control. Mutations of the two largest subunits, p89 (XPB) and p80 (XPD), cause the hereditary cancer-prone syndrome xeroderma pigmentosum. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|