Manipulation of sterol homeostasis for the production of 24-epi-ergosterol in industrial yeast

Autor: Yiqi Jiang, Zhijiao Sun, Kexin Lu, Zeyu Wu, Hailong Xue, Li Zhu, Guosi Li, Yun Feng, Mianbin Wu, Jianping Lin, Jiazhang Lian, Lirong Yang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36007-z
Popis: Brassinolide (BL) is one of the most active compounds among phytohormone brassinosteroids (BRs) and can be used for plant growth and development regulation. Here, the authors report the construction of an artificial pathway in baker’s yeast for scalable production of 24-epi-ergosterol, a precursor for BL semi-synthesis.
Databáze: Directory of Open Access Journals