Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study

Autor: Andreas K. Øvlisen, Anders Oest, Mette D. Bendtsen, John Bæch, Preben Johansen, Line S. Lynggaard, Ingolf Mølle, Thomas B. Mortensen, Duruta Weber, Gideon Ertner, Claudia Schöllkopf, Jesper Q. Thomassen, Ove Juul Nielsen, Lene Sofie Granfeldt Østgård, Martin Bøgsted, Karen Dybkær, Hans E. Johnsen, Marianne T. Severinsen
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Blood Advances, Vol 2, Iss 5, Pp 559-564 (2018)
Druh dokumentu: article
ISSN: 2473-9529
DOI: 10.1182/bloodadvances.2017007393
Popis: Abstract: Stringent complete remission (sCR) of acute myeloid leukemia is defined as normal hematopoiesis after therapy. Less sCR, including non-sCR, was introduced as insufficient blood platelet, neutrophil, or erythrocyte recovery. These latter characteristics were defined retrospectively as postremission transfusion dependency and were suggested to be of prognostic value. In the present report, we evaluated the prognostic impact of achieving sCR and non-sCR in the Danish National Acute Leukaemia Registry, including 769 patients registered with classical CR (ie,
Databáze: Directory of Open Access Journals