Long-lasting response with lapatinib treatment: a case report

Autor: Andrea Milani, Imperia Nuzzolese, Giovanna Chilà
Jazyk: English<br />Italian
Rok vydání: 2018
Předmět:
Zdroj: AboutOpen, Vol 4, Iss 1 (2018)
Druh dokumentu: article
ISSN: 2465-2628
DOI: 10.19156/abtpn.2018.0030
Popis: Lapatinib is a small molecule and a reversible inhibitor of HER2, which has shown to be effective on brain lesions in patients with HER2-positive breast cancer relapsed at the central nervous system (CNS). We report the clinical case of a young woman, treated with the combination of lapatinib and capecitabine from September 2009 to today for a metastatic recurrence of HER2-positive breast carcinoma at CNS level and who has achieved a complete response of the encephalic lesion and has not shown disease progression at systemic or CNS level, with excellent tolerance profile (Oncology).
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