Clozapine-induced liver injury and pleural effusion

Autor: Joseph P.M. Kane, Francis A. O’Neill
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Mental Illness, Vol 6, Iss 2 (2014)
Druh dokumentu: article
ISSN: 2036-7457
2036-7465
DOI: 10.4081/mi.2014.5403
Popis: Clozapine, whilst associated commonly with a transient and benign increase in liver enzymes, has also been associated with varying presentations of hepatitis in existing case reports. This report describes what we believe to be the first documented case of acute liver injury and pleural effusion associated with clozapine, resolving after cessation of the agent. The case supports existing literature in advocating a high index of suspicion, particularly in the 4-5 weeks following clozapine initiation, when considering nonspecific clinical symptoms and signs.
Databáze: Directory of Open Access Journals