Global longitudinal active strain energy density (GLASED): age and sex differences between young and veteran athletes

Autor: David H. MacIver, Henggui Zhang, Christopher Johnson, Efstathios Papatheodorou, Gemma Parry-Williams, Sanjay Sharma, David Oxborough
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Echo Research and Practice, Vol 11, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 2055-0464
DOI: 10.1186/s44156-024-00052-1
Popis: Abstract Background Global longitudinal active strain energy density (GLASED) is an innovative method for assessing myocardial function and quantifies the work performed per unit volume of the left ventricular myocardium. The GLASED, measured using MRI, is the best prognostic marker currently available. This study aimed to evaluate the feasibility of measuring the GLASED using echocardiography and to investigate potential differences in the GLASED among athletes based on age and sex. Methods An echocardiographic study was conducted with male controls, male and female young athletes, and male and female veteran athletes. GLASED was calculated from the myocardial stress and strain. Results The mean age (in years) of the young athletes was 21.6 for males and 21.4 for females, while the mean age of the veteran athletes was 53.5 for males and 54.2 for females. GLASED was found to be highest in young male athletes (2.40 kJ/m3) and lowest in female veterans (1.96 kJ/m3). Veteran males exhibited lower values (1.96 kJ/m3) than young male athletes did (P
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