| Autor: |
Niek van Wietmarschen, Sarra Merzouk, Nancy Halsema, Diana C. J. Spierings, Victor Guryev, Peter M. Lansdorp |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-02760-1 |
| Popis: |
Bloom syndrome is characterized by high levels of sister chromatid exchanges (SCEs). Here, the authors use single-cell DNA template strand-sequencing to map SCEs in patient cells, and propose that the BLM helicase protects the genome against unwanted recombination at sites of G-quadruplex structures. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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