Clinical factors affecting short- and long-term mortality in older patients with COVID-19: a retrospective cohort study
| Autor: | Benedetta Pennella, Francesca Rotunno, Martina Mercuri, Marco Guerci, Mauro Molteni, Marta Biancucci, Clelia Berton, Francesca Troian, Paolo Maria Tripodi, Alessia Gilio, Antea Milano, Daniela Dalla Gasperina, Francesco Dentali, Aldo Bonaventura, Andrea Maria Maresca |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Italian Journal of Medicine, Vol 18, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1877-9344 1877-9352 |
| DOI: | 10.4081/itjm.2024.1707 |
| Popis: | The majority of fatal cases of SARS-CoV-2 was concentrated among older patients. We aimed at assessing risk factors contributing to mortality in this population. A retrospective study including 584 COVID-19 patients aged ≥80 years hospitalized between October 10th 2020 to May 4th 2021 at Ospedale di Circolo (Varese, Italy) and Ospedale Galmarini (Tradate, Italy) was conducted. Evaluation of risk factors associated with in-hospital mortality was the primary endpoint. 509 patients were considered. Median age was 86 [82-89] years. Almost half of the patients (n=241) suffered from ≥3 comorbidities. Overall in-hospital mortality was 39.7% (n=202). Age, chronic kidney disease (CKD), peripheral oxygen saturation at admission, and high-flow oxygen during hospital stay independently predicted in-hospital mortality. Overall mortality at 6 months was 57.8% (n=294) and increased with increasing age and number of comorbidities (P |
| Databáze: | Directory of Open Access Journals |
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