Differential associations between body mass index and outcome in different age groups in patients with myocardial infarction

Autor: Vojko Kanic, Barbara Frank, Gregor Kompara, David Suran
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Indian Heart Journal, Vol 74, Iss 4, Pp 289-295 (2022)
Druh dokumentu: article
ISSN: 0019-4832
DOI: 10.1016/j.ihj.2022.06.004
Popis: Objective: To investigate the association between age and body mass index (BMI) and mortality in patients with myocardial infarction (MI). Methods We divided 6453 patients into three age groups (75 years) and five BMI categories. Thirty-day and long-term all-cause mortality were assessed. Results: No association was found between the BMI category and 30-day mortality in any age group. The association between BMI and long-term multivariable-adjusted mortality risk was age-dependent. Overweight patients had a lower risk than patients with BMI 75 years, respectively). The lower risk of death as a function of BMI shifted upward with age, and the risk was also lower in patients with obesity grade I (HR 0.81; 95% CI 0.66–0.98; p = 0.035 and HR 0.78; 95% CI 0.63–0.97; p = 0.023 for ages 60–75, >75 years, respectively). Excessive obesity was harmful only in the oldest group. Patients with obesity grade III had more than a 2.5 times higher mortality risk than patients with BMI
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