Acute tolerance to rocuronium -A case report
| Autor: | Jong Ho Kim, Sang joon Park, Youngsuk Kwon, Sung Mi Hwang, Hong Seuk Yang |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Anesthesia and Pain Medicine, Vol 19, Iss 4, Pp 333-338 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1975-5171 2383-7977 |
| DOI: | 10.17085/apm.24064 |
| Popis: | Background A booster dose can result in a similar reaction to the initial dose. Neuromuscular blocking agents (NMBAs) can produce a comparable reaction in the absence of specific pathophysiologic alterations. Case An initial dose of rocuronium 40 mg was given to a male patient (50 years old, height 168 cm, weight 54 kg, body mass index 19.13 kg/m2) for anesthesia. The onset was usual, but the duration was brief. Two booster doses were administered at 20 min intervals, but recovery came quickly. So, acute tolerance was suspected. Muscle function was restored to greater than train-of-four ratio 0.75 while spontaneous aided breathing was maintained without the need of further NMBAs. Following the operation, sugammadex (1.85 mg/kg) was provided to prevent residual neuromuscular inhibition. Conclusions Anesthetists must be able to suspect acute tolerance to NMBAs in patients with no unique medical history and have a plan to resolve it. |
| Databáze: | Directory of Open Access Journals |
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