The Evaluation of New Generation Inflammatory Markers in Children With Morbid Obesity and Metabolic Syndrome

Autor: Mustafa Metin DONMA, Sevgi Dilan ERSELCAN, Ahsen YILMAZ, Savaş GUZEL, Orkide DONMA
Jazyk: English<br />Turkish
Rok vydání: 2020
Předmět:
Zdroj: Namık Kemal Tıp Dergisi, Vol 8, Iss 3, Pp 479-488 (2020)
Druh dokumentu: article
ISSN: 2587-0262
DOI: 10.37696/nkmj.781963
Popis: Aim: Technological advancements, unbalanced nutrition, sedentary life style, are important factors in obesity. Obesity-inflammation relationis beingexamined. In this study, the relationships among new generation inflammatory markers in children with normal body mass index (C) as well as obese (OB), morbid obese (MO) children and those with metabolic syndrome (MetS) were investigated.Materials and Methods: A total of 172 children participated in the study.Group 1 comprised children with normal body-mass index (control group) (C). Obese (OB) children were in Group 2, MO children constituted Group 3 and Group 4 included MO children with MetS. The number of cases were 37, 34, 51 and 50 in groups 1, 2, 3 and 4, respectively. Anthropometric measurements were recorded. Serum spexin, adropin, adipolipin, fibroblast growth factor-21 and fetuin-A levels were determined. Statistical analyses were performed.Result:Spexin and adipolin levels were significantly lower in obese groups than C group (p
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