| Autor: |
Seiji Fukamizu, MD, Harumizu Sakurada, MD, Makoto Takano, MD, Rintarou Hojo, MD, Mori Nakai, MD, Takao Yuba, MD, Kota Komiyama, MD, Akiko Tatsumoto, MD, Kenichi Maeno, MD, Yuka Mizusawa, MD, Yasuhiro Tanabe, MD, Makoto Suzuki, MD, Tamotsu Tejima, MD, Mitsuhiro Nishizaki, MD, Youichi Kobayashi, MD, Masayasu Hiraoka, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Journal of Arrhythmia, Vol 26, Iss 1, Pp 21-29 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
1880-4276 |
| DOI: |
10.1016/S1880-4276(10)80032-8 |
| Popis: |
Introduction: Previous studies have shown that atrial fibrillation (AF) recurrence after pulmonary vein (PV) isolation depends on various factors; however, the effect of cigarette smoking on AF recurrence after PV isolation has not been investigated. Methods and Results: Fifty-nine consecutive patients with drug-refractory AF (48 men and 11 women, mean age: 60 ± 11 years) who underwent PV isolation were included. The patients were divided into two groups: the non-smoker group, i.e., “never smokers (n = 29),” and the smoker group consisting of 30 patients who were either “former smokers (n = 15)” or “current smokers (n = 15)”. The diameter of all four PVs and the left atrial volume tended to be larger in the smoker group. During the mean follow-up period of 306 ± 95 days, the AF recurrence rate was higher in the smoker group than in the non-smoker group (43% vs. 14%, p < 0.05). The relative risk of AF recurrence associated with smoking was 3.19 (95% CI 1.23 to 8.27, p = 0.017). The AF recurrence rate was increased in both current smokers (40%) and former smokers (47%) compared to never smokers (14%). Conclusions: AF recurrence after PV isolation was significantly higher in the smoking patients. The substrate of AF may be worsened by exposure to cigarette smoking. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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