Association of sex, age and education level with patient reported outcomes in atrial fibrillation

Autor: Kelly T. Gleason, Cheryl R. Dennison Himmelfarb, Daniel E. Ford, Harold Lehmann, Laura Samuel, Hae Ra Han, Sandeep K. Jain, Gerald V. Naccarelli, Vikas Aggarwal, Saman Nazarian
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-12 (2019)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-019-1059-6
Popis: Abstract Background In atrial fibrillation (AF), there are known sex and sociodemographic disparities in clinical outcomes such as stroke. We investigate whether disparities also exist with respect to patient-reported outcomes. We explored the association of sex, age, and education level with patient-reported outcomes (AF-related quality of life, symptom severity, and emotional and functional status). Methods The PaTH AF cohort study recruited participants (N = 953) with an AF diagnosis and age ≥ 18 years across 4 academic medical centers. We performed longitudinal multiple regression with random effects to determine if individual characteristics were associated with patient-reported outcomes. Results Women reported poorer functional status (β − 2.23, 95% CI: -3.52, − 0.94) and AF-related quality of life (β − 4.12, 95% CI: -8.10, − 0.14), and higher symptoms of anxiety (β 2.08, 95% CI: 0.76, 3.40), depression (β 1.44, 95% CI: 0.25, 2.63), and AF (β 0.29, 95% CI: 0.08, 0.50). Individuals
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