| Autor: |
Nikki Emamian, Taylor Miller, Zoe Glick, Lauren Day, Lauren Becker, Aditi Singh, Tesia Shi, Jeffrey Rea, Kimberly Boswell, Quincy K. Tran |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 5, Pp n/a-n/a (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2688-1152 |
| DOI: |
10.1002/emp2.13281 |
| Popis: |
Abstract Objectives We hypothesized that lactate clearance and reduction of the Sequential Organ Failure Assessment (SOFA) score during patients’ critical care resuscitation unit (CCRU) stay would be associated with lower in‐hospital mortality. Methods This was a retrospective study of adult patients who had sepsis diagnoses and were admitted to the CCRU in 2018. Multivariable logistic regression analysis was performed to assess the association of clinical factors, lactate clearance, and SOFA reduction with hospital mortality. Results A total of 401 patients with lactate clearance data and 455 patients with SOFA score data were included in the study. The mean (SD) lactate and SOFA score on admission were 2.2 (1.8) mmol/L and 4.4 (4.3), respectively. Average lactate clearance was 0.1 (2.6) mmol/L, and average SOFA score reduction was 0.65 (5.9). Patients with a one point reduction in SOFA score during their CCRU stay had a 31% reduction of mortality (odds ratio [OR] 0.69, 95% confidence interval [CI] 0.62–0.77, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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