Dynapenia could predict chemotherapy-induced dose-limiting neurotoxicity in digestive cancer patients

Autor:	Damien Botsen, Marie-Amélie Ordan, Coralie Barbe, Camille Mazza, Marine Perrier, Johanna Moreau, Mathilde Brasseur, Yohann Renard, Barbara Taillière, Florian Slimano, Eric Bertin, Olivier Bouché
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Dynapenia Antineoplastic agents Digestive system neoplasms Sarcopenia Dose-limiting toxicity Muscle strength Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-018-4860-1
Popis:	Abstract Background FIGHTDIGO study showed the feasibility and acceptability of handgrip strength (HGS) measure in routine in 201 consecutive patients with digestive cancer treated with ambulatory chemotherapy. The present study focuses on the second aim of FIGHTDIGO study: the relationships between pre-therapeutic dynapenia and chemotherapy-induced Dose-Limiting Toxicities (DLT). Methods In this ancillary prospective study, DLT were analyzed in a sub-group of 45 chemotherapy-naive patients. Two bilateral consecutive measures of HGS were performed with a Jamar dynamometer before the first cycle of chemotherapy. Dynapenia was defined as HGS
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/611d0a8e75d74673a766e666e6e4d326 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.